MUCOMYST may also be given through a percutaneous intratracheal catheter. Two to 5 mL of the 20% solution may then be instilled by means of a syringe connected to the catheter. MUCOMYST may be introduced directly into a particular segment of the bronchopulmonary tree by inserting (under local anesthesia and direct vision) a small plastic catheter into the trachea. When used for the routine nursing care of patients with tracheostomy, 1 to 2 mL of a 10% to 20% solution may be given every 1 to 4 hours by instillation into the tracheostomy. When used by direct instillation, 1 to 2 mL of a 10% to 20% solution may be given as often as every hour. Administration for intermittent or continuous prolonged periods, including overnight, may be desirable. If a tent or Croupette must be used, the recommended dose is the volume of MUCOMYST (using 10% or 20%) that will maintain a very heavy mist in the tent or Croupette for the desired period. This form of administration requires very large volumes of the solution, occasionally as much as 300 mL during a single treatment period. In special circumstances it may be necessary to nebulize into a tent or Croupette, and this method of use must be individualized to take into account the available equipment and the patient's particular needs. When nebulized into a face mask, mouth piece, or tracheostomy, 1 to 10 mL of the 20% solution or 2 to 20 mL of the 10% solution may be given every 2 to 6 hours the recommended dose for most patients is 3 to 5 mL of the 20% solution or 6 to 10 mL of the 10% solution 3 to 4 times a day. NEBULIZATION-FACE MASK, MOUTH PIECE, TRACHEOSTOMY If only a portion of the solution in a vial is used, store the remainder in a refrigerator and use for inhalation only within 96 hours. MUCOMYST does not contain an antimicrobial agent, and care must be taken to minimize contamination of the sterile solution. The 20% solution may be diluted to a lesser concentration with either Sodium Chloride for Injection, Sodium Chloride for Inhalation, Sterile Water for Injection, or Sterile Water for Inhalation. MUCOMYST is available in rubber stoppered glass vials containing 4, 10, or 30 mL. It is essential to initiate treatment as soon as possible after the overdose and, in any case, within 24 hours of ingestion. Pulmonary complications associated with surgeryĭiagnostic bronchial studies (bronchograms, bronchospirometry, and bronchial wedge catheterization)Īcetylcysteine, administered orally, is indicated as an antidote to prevent or lessen hepatic injury which may occur following the ingestion of a potentially hepatotoxic quantity of acetaminophen. Pulmonary complications of cystic fibrosis MUCOMYST is indicated as adjuvant therapy for patients with abnormal, viscid, or inspissated mucous secretions in such conditions as:Ĭhronic bronchopulmonary disease (chronic emphysema, emphysema with bronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis and primary amyloidosis of the lung)Īcute bronchopulmonary disease (pneumonia, bronchitis, tracheobronchitis) Summary Description and Clinical Pharmacology Indications and Dosage Warnings and Precautions Side Effects and Adverse Reactions Drug Interactions, Overdosage, Contraindications, Other Rx Info Side Effect Reports Rx drug information, pharmaceutical research, clinical trials, news, and more If you combine a blood thinner with acetaminophen, be sure to report any signs of bleeding to your health care provider, including pain, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, unexpected vaginal bleeding, nosebleeds, gum bleeding, unusual bruising, red or dark urine, or red or black (tarry) stools.Mucomyst (Acetylcysteine Inhalation) - Indications and Dosage However, if you take a blood thinner, be sure to check with your doctor or pharmacist before taking acetaminophen long-term or in high doses as acetaminophen may lead to bleeding. Acetaminophen typically has a lower effect on inflammatory pain than NSAIDs.Īcetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.Īcetaminophen does not inhibit thromboxane and does not alter platelet aggregation, like aspirin, therefore it is usually the pain reliever of choice for patients who take a blood thinner. It is hypothesized that acetaminophen may inhibit COX enzymes, similar to the way NSAIDs work, but without the anti-inflammatory component. Acetaminophen is classified as a miscellaneous analgesic for mild to moderate pain and fever. No, acetaminophen (Tylenol) is not classified as an NSAID (nonsteroidal anti-inflammatory drug).
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